YOSHIKI Explores Wellness with Nobel Prize Candidates: Autophagy & Sleep Science Broadcast

In the second episode of YOSHIKI CHANNEL’s “Wellness and Beauty” series, YOSHIKI engages in deep, thought-provoking dialogue with two of the most respected names in modern medical science. This double-feature livestream highlights the latest research in autophagy and sleep science, blending scientific insight with personal reflection.

Part 1: Understanding Autophagy – Featuring Dr. Tamotsu Yoshimori

‍YOSHIKI​ Channel's first guest is Dr. Tamotsu Yoshimori, one of the world’s foremost experts in autophagy and widely considered a leading candidate for the Nobel Prize, with pioneering discoveries that have shaped global biomedical research.

In this segment, Dr. Yoshimori breaks down how autophagy serves as the body’s natural cleansing system—removing damaged cellular components, reducing inflammation, and promoting longevity. He also explains how fasting and caloric restriction can activate this process. YOSHIKI connects this science to his own highly disciplined lifestyle, sharing how his health routines and creative discipline align with these principles.

Part 2: Sleep Science and Mental Health – Featuring Dr. Masashi Yanagisawa

‍The second part of the broadcast features Dr. Masashi Yanagisawa, internationally recognized as a top Nobel Prize candidate in Physiology or Medicine. His landmark discovery of orexin—a neuropeptide critical to sleep regulation—and the neurobiological basis of narcolepsy earned him the 2023 Breakthrough Prize and selection as a Clarivate Citation Laureate, an accolade that has historically predicted future Nobel laureates.

Dr. Yanagisawa discusses the fundamental importance of sleep quality, not just duration, and how factors like artificial light, screen use, and irregular schedules can disrupt the brain’s natural rhythm. YOSHIKI reflects on the challenges of maintaining good sleep hygiene amid an intense global schedule and shares his personal strategies for recovery and rest.

By sitting down with two of the most accomplished minds in modern science—both regarded as potential future Nobel laureates —YOSHIKI brings health and wellness to the forefront of public conversation. This special edition of the Wellness and Beauty series bridges scientific understanding with personal experience, making complex topics both engaging and accessible. As both an artist and advocate, YOSHIKI continues to inspire global audiences to pursue healthier, more balanced lives grounded in knowledge, intention, and curiosity.